Topic > The blood type - 1105

IntroductionThere are many important details and information that the healthcare provider should know about the patient before performing any procedure or prescribing a drug. One of this information is blood type. The first blood groups were discovered by Karl Landsteiner in 1901. Landsteiner was studying the fact that some blood transfusions were successful and others could be potentially lethal. He conducted research in which he demonstrated that the serum of one people leads in some cases to the agglutination of the blood cells of others, but in others the agglutination did not occur. In his experiments he discovered the first three blood types A, B and O. Later Landsteiner and the American researcher Alexander Wiener discovered the new blood group Rh, which was reported in 1940, 1941. (Farhud, 2013) The blood group is defined by presence or absence of certain antigens on the surface of red blood cells (RBCs) called A, B, O or Rh (D) antigens. Depending on the antigen present on the plasma membrane of the red blood cells, the person will have certain antibodies present in the plasma. Blood type A has antibodies to type B blood. Type B blood has anti-A antibodies, and type O blood has antibodies to A and B. Knowing the patient's blood type information is extremely important during transfusion of blood because the antibodies of some blood groups attack the antigens present on the red blood cells of foreign blood causing agglutination - aggregation of the red blood cells. So blood cells with A antigen on the surface membrane will be affected by A antibodies, red blood cells with B antigen will react with B antibodies, and red blood cells with Rh antigen will react with Rh antibodies. If the type A recipient is given blood containing A antibodies (types B and O) agglutination will occur and a lethal outcome is possible. It is important that the central part of the sheet is AB+. Table 2 summarizes the conclusions reached in this experiment. Table 2 Sample 1 Sample 3 Sample 4 Sample 5 Blood type A+ B+ B- AB+ During this workshop general blood typing techniques were studied and students became familiar with blood types and how to identify them. All members of the study team followed the procedure to avoid cross-contamination, so the results are considered accurate. This lab provided excellent visualization of agglutination and a better understanding of this process. Overall, blood typing has wide application in healthcare. Examples may be blood typing performed before blood transfusion, during pregnancy, or blood typing for research and better understanding of blood-related disorders. Such broad application of these techniques makes them important to study by all students considering a career in medicine.