Symptoms of hyponatremia differ from individual to individual depending on the severity. Most symptoms begin with lethargy even at mild levels. Individuals may often suffer from stomach pain, drowsiness, and vomiting. Hospitalization usually involves severe symptoms such as lethargy, lack of orientation in time and space, and an altered state of consciousness. After hospitalization, routine blood tests are completed to determine the initial causes of these symptoms. If results show sodium levels below the reference range of 135-145 mEq/L, patients are considered to be in a hyponatremic state (Pietrini 2010). These symptoms often worsen during treatment with hypertonic saline and, in turn, can initiate the development of CPM. Patients begin to improve and become more alert after starting treatment of hyponatremia. Neurological conditions often improve gradually. However, with treatment sodium levels return to normal as the patient achieves normatremia. At this time, the development of more severe symptoms requires further examination and testing. Symptoms of CPM have been observed 3-10 days after treatment of hyponatremia when patients reach normatremia. Restlessness and confusion are key symptoms in individuals who have recently undergone rapid treatment of hyponatremia. CPM-associated lesions are believed to begin to develop when normatremia is achieved too quickly. Once patients reach normatremia, as discussed above, new symptoms develop and require a neurological examination to be performed. At the end of the examination, moderate quadriparesis, bilateral tremor and limb dysmetria, i.e. the lack of coordination in the control of muscle movement, were found. At the same time, an MRI can be performed and... in the center of the paper... the white matter of the brain. It is also important for determining early-onset pathological changes. CT and DWI scans are important testing techniques used to determine the initial causes of neurological changes in individuals. However, currently the best available testing method for identifying CPM is magnetic resonance imaging (MRI). With the use of strong magnetic fields and radio waves in MRI, accurate body images are produced. MRI scans are highly sensitive and offer better contrast visualization of gray and white matter in the brain. MRI is the optimal choice for testing for diseases and/or disorders of the central nervous system. The optimal time to perform an MRI is also the most critical time to perform the scan, when patients develop neurological symptoms. The diagnosis is generally confirmed by autopsy results (Gheorghita et. al 2010).