The Effectiveness of Therapeutic Touch Compared to the poor evidence base for tactile touch, therapeutic touch has recently proven applicable in a variety of different populations and contexts in recent years. In this part, eight experimental research and four qualitative research are explored. TT is safe and effective to implement on hospitalized patients. Newshan & Schuller-Civitella (2003) conducted a large-scale study on 605 patients from 1998 to 2000. 48% of patients (n=259) reported a reduction in painful suffering. 48% of patients (n=254) were found to have a physiological response related to relaxation; 90% (n=83) of patients rated the TT as “very helpful” or “helpful.” 12% (n=605) of patients reported no change and 20% fell asleep during TT sessions. However, the lack of a predetermined TT treatment time and comparison group, self-administered questionnaire, and convenience sample limited the generalizability of this study. TT may be useful as an additional measure to lower anxiety levels and reduce chemical dependency withdrawal symptoms. Larden et al. (2004) undertook a three-group RCT to study the effects of TT on hospitalized pregnant women with chemical dependency. 42 of 54 women completed the study and only 16 received consecutive 7-day treatments. A lower level of anxiety was found in the TT group compared to the in-person group and the standard care group (p=0.27) in the first three days of intervention. Short-term treatments, high attrition rate (22%), inability to blind participants, small sample size could contribute to the insignificant change in mean symptom score. TT could facilitate the mind-body connection. Movaffaghi & Farsi (2006) used a double-blind RCT to examine the TT effect… half of the article… the speed of blinded participants; inconsistent data collectors resulting in incomplete data sets; convenience sample; Inappropriate recording times and placebo effects can create a therapeutic participant relationship that makes the scientific study of measuring tactile therapies problematic (O'Regan et al., 2010). Above all, invalidated measurements especially for subjective parameters and different time duration of the TT session are also common shortcomings in all studies. Precautions in performing tactile therapies There are various factors that exert an influential effect on tactile performance, including external contextual variables and internal characters of patients. Harrison et al. (2012) found that the effects of touch could be beneficial or harmful depending on myriad client and contextual and professional variations. Environmental influences: