Topic > Embryonic Stem Cells - 1262

Since the advent of embryonic stem cells, scientists around the world have sought to come to terms with the infinite possibilities these cells hold, harnessing them to create synthetic organs and cure previously incurable diseases. However, embryonic stem cells face a lot of opposition in terms of the ethics involved in obtaining these cells from both embryos and mothers, as well as the possible health risks associated with them. Even so, this field shows much promise and should not be ignored solely because of these issues. Human embryonic stem cells (hESCs) have a rare senescent ability to divide infinitely (Rippon & Bishop, 2004) and to differentiate into any cell type (they are pluripotent). As the name suggests, they are derived from excess embryos or blastocysts from in vitro fertilization treatments (Fig. 1); specifically from the inner cell mass, a small group of 30 cells in the hollow blastocyst (Rippon & Bishop, 2004). These cells are then grown on a nutrient-rich sterile inert culture medium and incubated at 37℃ (to maintain optimal temperature for various processes) with oxygen (LeCornu & Diercks 2009) and passaged after reaching adequate confluence, thus preventing contact inhibition ( Stevenson, 2009 ). Furthermore, since hESCs have a tendency to differentiate spontaneously, they are often cultured with feeder cells (MEFs) that provide them with LIF (leukemia inhibitory factor), a growth factor responsible for inhibiting the differentiation of hESCs, while allowing them to proliferate (Niwa, 2004). ). After large numbers of hESCs have formed, they can be cultured with certain growth factors and stimulated to differentiate into specific cells. These cells can then be used in the regenerative treatment of various diseases and even to synthesize… middle of paper… ancestors) developed in grafted human tissue injected with hESCs, the likelihood that hESCs cause “aggressive” effects tumors” (Verloes et. al., 2011) in humans has increased. This possibility of hESCs turning into cancer seriously calls into question patient safety, raising concerns about the safety of such a new technology. However, such scientific problems will be overcome with technological advances and further research, and most people believe that the ethical obligation to preserve current life, and the economic and social benefits that flow from it, far outweigh the moral injustices resulting from the destruction of embryos in the face of death and large-scale suffering caused by disease, embryonic stem cell treatments (regenerative treatment and therapeutic cloning) could mark a new beginning for society and a new solution. A solution only possible with further research.